Abivax Reports Promising ABX464 Phase 2a One-Year Maintenance Results in Rheumatoid Arthritis

Below is a press release dated today (3/10/22) from Abivax:

The Quick Basics

Out of the 40 patients who enrolled into the ABX464 maintenance study, 23 patients have now reached the first year of treatment and all achieved at least an ACR201, with 19 and 12 patients achieving ACR50 and ACR70 respectively.

Long-term safety profile (50mg ABX464 once daily + MTX) favorable and consistent with previous observations.

The induction and maintenance results support further clinical development of ABX464 in RA and potentially other rheumatology indications.

The clinical induction and maintenance data in ulcerative colitis and rheumatoid arthritis underpin the potential of ABX464 to address a broad range of chronic inflammatory diseases.

In G7 countries, the market for ulcerative colitis, Crohn’s disease and rheumatoid arthritis is expected to grow to approximately USD 50B in 2026.

The Full Press Release

Abivax SA (Euronext Paris: FR0012333284 – ABVX), a clinical-stage biotechnology company developing novel therapies that modulate the immune system to treat chronic inflammatory diseases, viral infections, and cancer, today reports promising results from its phase 2a maintenance trial in rheumatoid arthritis (RA) after one year of continued daily treatment with 50mg ABX464.

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Autoimmune Community Institute to Host Inaugural Autoimmune Health Equity Summit [postponed]

Update:

With deep sadness, the Autoimmune Community Institute announces today that we must postpone the Inaugural Autoimmune Health Equity Summit originally planned for Saturday, March 12 due to technical issues. 

While compiling our pre-recorded interviews to create the final product, we noticed that the video from some of our amazing speakers did not record. This error is not one that could have been foreseen or prevented, as this is the first time an error like this has occurred. As a result, we felt it necessary to postpone the event to rectify these issues and ensure our speakers can be seen and heard properly.

Dr. April Moreno, Founder at Autoimmune Community Institute has provided the following statement:

“Unfortunately, we experienced technical difficulties with the video service platform and will need time to correct some of the recordings for the event.”

Despite these unfortunate setbacks, registration will continue to be open for the postponed event, which will now occur on March 19, 2022, at 12pm Pacific Time (3pm Eastern Time. We continue to look forward to hosting the event and apologize again for any inconvenience or disappointment. 

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The following is a press release dated March 7 from the Autoimmune Community Institute.

The Autoimmune Community Institute is dedicated to autoimmune health equity through community-based research and support services. The all-volunteer team strives to fulfill that mission by creating spaces for diverse autoimmune voices and experiences in community-centered research design, community support, and health equity advocacy every single day.

Today, ACI is taking a momentous step to further its mission and fulfill its goals by announcing the Inaugural Autoimmune Health Equity Summit. The ACI Health Equity Summit is our signature event to highlight the importance of diversity and representation in autoimmune communities.

This free event will discuss the importance of diversity and representation in research, policy, advocacy, and community support services; as well as the difference between equality and health equity and why we must work toward equity in all policies. Participants will also be introduced to some of our excellent partners in autoimmune health serving diverse communities.

The summit is designed for autoimmune patients, clinicians, researchers, and anyone who works with or has an interest in autoimmune topics. It will be held on March 12, 2022, at 12 pm Pacific Time (3 pm Eastern Time). Registration for the event is now open here

Please share this event widely within your networks. The staff at ACI is extremely excited to be hosting this event, and cannot wait to see you there!

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